CONNEXIN 26 MUTATIONS ASSOCIATED WITH RECESSIVE NON SYNDROMIC SENSORINEURAL DEAFNESS IN SUB-SAHARAN AFRICAN PATIENTS
Masters Student: Jason Bosch
There is very little research on non-syndromic sensorineural hearing loss in African populations. Studies elsewhere have shown that mutations leading to hearing loss are population specific.
- To clarify the pattern of GJB2 mutations in a selected sample of African patients, from both South Africa and Cameroon, with non-syndromic, sensorineural hearing loss.
- To explore mutations in GJA1/Connexin 43 and GJB6/Connexin 30.
- To explore mutations in mitochondrial genes.